Publications
- Probing the Assembly of HDL Mimetic, Drug Carrying Nanoparticles, using Intrinsic Fluorescence Raut SG, Garud A, Nagarajan B, Sabnis N, Remaley A, Fudala R, Gryczynski I, Gryczynski Z, Dzyuba SV, Borejdo J, Lacko AG. J Pharmacol Exp Ther. 2020 Jan 15;jpet.119.262899. doi: 10.1124/jpet.119.262899. [Epub ahead of print]. PMID: 31941718.
- Identifying and targeting angiogenesis-related microRNAs in ovarian cancer. Chen X, Mangala LS, Mooberry L, Bayraktar E, Dasari SK, Ma S, Ivan C, Court KA, Rodriguez-Aguayo C, Bayraktar R, Raut S, Sabnis N, Kong X, Yang X, Lopez-Berestein G, Lacko AG, Sood AK.Oncogene. 2019 Aug;38(33):6095-6108. doi: 10.1038/s41388-019-0862-y. Epub 2019 Jul 9.
- The SR-B1 Receptor as a Potential Target for Treating Glioblastoma.Berney E, Sabnis N, Panchoo M, Raut S, Dickerman R, Lacko AG. J Oncol. 2019 Jun 3;2019:1805841. doi: 10.1155/2019/1805841. eCollection 2019.
- Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells. Shelake S, Sankpal UT, Eslin D, Bowman WP, Simecka JW, Raut S, Ray A, Basha R. Apoptosis. 2019 Feb;24(1-2):21-32. doi: 10.1007/s10495-018-1508-1
- [99mTc-HYNIC-N-dodecylamide]: a new hydrophobic tracer for labelling reconstituted high-density lipoproteins (rHDL) for radioimaging. Isaac-Olivé K, Ocampo-García BE, Aranda-Lara L, Santos-Cuevas CL, Jiménez-Mancilla NP, Luna-Gutiérrez MA, Medina LA, Nagarajan B, Sabnis N, Raut S, Prokai L, Lacko AG. Nanoscale. 2019 Jan 3;11(2):541-551. doi: 10.1039/c8nr07484d.
- Reconstituted HDL: Drug Delivery Platform for Overcoming Biological Barriers to Cancer Therapy. Raut S, Mooberry L, Sabnis N, Garud A, Dossou AS, Lacko A. Front Pharmacol. 2018 Oct 15;9:1154. doi: 10.3389/fphar.2018.01154. eCollection 2018. Review
- Enhanced DNA detection using a multiple pulse pumping scheme with time-gating (MPPTG). Kimball JD, Maliwal B, Raut SL, Doan H, Nurekeyev Z, Gryczynski I, Gryczynski Z., Analyst. 2018 Jun 11;143(12):2819-2827. doi: 10.1039/c8an00136g.29774908
- Lipoproteins for therapeutic delivery: recent advances and future opportunities. Raut S, Dasseux JL, Sabnis NA, Mooberry L, Lacko A. Ther Deliv. 2018 Mar 2. doi: 10.4155/tde-2017-0122. [Epub ahead of print]
- Scavenger receptor class B type 1 regulates neuroblastoma cell proliferation, migration and invasion. Panchoo M, Lacko A. Biochem Biophys Res Commun. 2017 Nov 8. pii: S0006-291X(17)32141-1. doi: 10.1016/j.bbrc.2017.10.154. [Epub ahead of print]PMID: 29128352
- SR-B1-targeted nanodelivery of anti-cancer agents: a promising new approach to treat triple-negative breast cancer.Johnson R, Sabnis N, Sun X, Ahluwalia R, Lacko AG. Breast Cancer (Dove Med Press). 2017 Jun 2;9:383-392. doi: 10.2147/BCTT.S131038. eCollection 2017.PMID:28670138
- Fluorescence properties of doxorubicin in PBS buffer and PVA films. Shah S, Chandra A, Kaur A, Sabnis N, Lacko A, Gryczynski Z, Fudala R, Gryczynski I. J Photochem Photobiol B. 2017 May;170:65-69. doi: 10.1016/j.jphotobiol.2017.03.024. Epub 2017 Mar 30.PMID:28390260
- Superparamagnetic reconstituted high-density lipoprotein nanocarriers for magnetically guided drug delivery. Sabnis S, Sabnis NA, Raut S, Lacko AG. Int J Nanomedicine. 2017 Feb 22;12:1453-1464. doi: 10.2147/IJN.S122036. eCollection 2017. PMID:28260891
- Targeting the SR-B1 Receptor as a Gateway for Cancer Therapy and Imaging. Mooberry LK, Sabnis NA, Panchoo M, Nagarajan B, Lacko AG. Front Pharmacol. 2016 Dec 15;7:466. doi: 10.3389/fphar.2016.00466. eCollection 2016. Review. PMID:28018216
- Photophysical characterization of anticancer drug valrubicin in rHDL nanoparticles and its use as an imaging agent. Shah S, Chib R, Raut S, Bermudez J, Sabnis N, Duggal D, Kimball JD, Lacko AG, Gryczynski Z, Gryczynski I. J Photochem Photobiol B. 2016 Feb;155:60-5. doi: 10.1016/j.jphotobiol.2015.12.007. Epub 2015 Dec 18.
- HDL as a drug and nucleic acid delivery vehicle. Lacko AG, Sabnis NA, Nagarajan B, McConathy WJ.Front Pharmacol. 2015 Oct 26;6:247. doi: 10.3389/fphar.2015.00247. eCollection 2015. Review. PMID:26578957
- Targeted nanoparticles for pediatric leukemia therapy. Basha R, Sabnis N, Heym K, Bowman WP, Lacko AG. Front Oncol. 2014 May 13;4:101. doi: 10.3389/fonc.2014.00101. eCollection 2014. Review. PMID:24860784
- Pre-Clinical Evaluation of rHDL Encapsulated Retinoids for the Treatment of Neuroblastoma. Sabnis N, Pratap S, Akopova I, Bowman PW, Lacko AG. Front Pediatr. 2013 Mar 21;1:6. doi: 10.3389/fped.2013.00006. eCollection 2013 Mar 21.PMID:24459664
- The potential role of nanotechnology in therapeutic approaches for triple negative breast cancer. Johnson R, Sabnis N, McConathy WJ, Lacko AG. Pharmaceutics. 2013;5(2):353-70. doi: 10.3390/pharmaceutics5020353.PMID:24244833
- The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics. Cruz PM, Mo H, McConathy WJ, Sabnis N, Lacko AG. Front Pharmacol. 2013 Sep 25;4:119. doi: 10.3389/fphar.2013.00119. Review.PMID:24093019
- Drug delivery via lipoprotein-based carriers: answering the challenges in systemic therapeutics. Sabnis N, Lacko AG. Ther Deliv. 2012 May;3(5):599-608. Review. Erratum in: Ther Deliv. 2012 Jun;3(6):800.PMID:22834404
- Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles. Sabnis N, Nair M, Israel M, McConathy WJ, Lacko AG. Int J Nanomedicine. 2012;7:975-83. doi: 10.2147/IJN.S28029. Epub 2012 Feb 22.PMID:22393294
- Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles. Shahzad MM, Mangala LS, Han HD, Lu C, Bottsford-Miller J, Nishimura M, Mora EM, Lee JW, Stone RL, Pecot CV, Thanapprapasr D, Roh JW, Gaur P, Nair MP, Park YY, Sabnis N, Deavers MT, Lee JS, Ellis LM, Lopez-Berestein G, McConathy WJ, Prokai L, Lacko AG, Sood AK. Neoplasia. 2011 Apr;13(4):309-19.PMID:21472135
- Validation of the reconstituted high-density lipoprotein (rHDL) drug delivery platform using dilauryl fluorescein (DLF).McConathy WJ, Paranjape S, Mooberry L, Buttreddy S, Nair M, Lacko AG. Drug Deliv Transl Res. 2011 Apr;1(2):113-20. doi: 10.1007/s13346-010-0012-0. PMID:25788110
- Studies on solvatochromic properties of aminophenylstyryl-quinolinum dye, LDS 798, and its application in studying submicron lipid based structure. Sarkar P, Luchowski R, Raut S, Sabnis N, Remaley A, Lacko AG, Thamake S, Gryczynski Z, Gryczynski I. Biophys Chem. 2010 Dec;153(1):61-9. doi: 10.1016/j.bpc.2010.10.005. Epub 2010 Oct 13. PMID:21041016
- Receptor mediated uptake of paclitaxel from a synthetic high density lipoprotein nanocarrier. Mooberry LK, Nair M, Paranjape S, McConathy WJ, Lacko AG. J Drug Target. 2010 Jan;18(1):53-8. doi: 10.3109/10611860903156419. PMID:19637935
- Binding of 8-anilino-1-naphthalenesulfonate to lecithin:cholesterol acyltransferase studied by fluorescence techniques. Sarkar P, Bharill S, Gryczynski I, Gryczynski Z, Nair MP, Lacko AG. J Photochem Photobiol B. 2008 Jul 24;92(1):19-23. doi: 10.1016/j.jphotobiol.2008.03.009. Epub 2008 Apr 7. PMID:18485727
- Evaluation of synthetic/reconstituted high-density lipoproteins as delivery vehicles for paclitaxel. McConathy WJ, Nair MP, Paranjape S, Mooberry L, Lacko AG. Anticancer Drugs. 2008 Feb;19(2):183-8. doi: 10.1097/CAD.0b013e3282f1da86. PMID:18176115
- Prospects and challenges of the development of lipoprotein-based formulations for anti-cancer drugs. Lacko AG, Nair M, Prokai L, McConathy WJ. Expert Opin Drug Deliv. 2007 Nov;4(6):665-75. Review. PMID:17970668
- Doxorubicin transport by RALBP1 and ABCG2 in lung and breast cancer. Singhal SS, Singhal J, Nair MP, Lacko AG, Awasthi YC, Awasthi S. Int J Oncol. 2007 Mar;30(3):717-25.PMID:17273774
- Recent developments and patenting of lipoprotein based formulations. Lackó AG, Stewart DR, McClain R, Prókai L, McConathy WJ. Recent Pat Drug Deliv Formul. 2007;1(2):143-5. Review. PMID:19075881
- Structural differences between wild-type and fish eye disease mutant of lecithin:cholesterol acyltransferase. Reshetnyak Y, Tchedre KT, Nair MP, Pritchard PH, Lacko AG. J Biomol Struct Dyn. 2006 Aug;24(1):75-82. PMID:16780378
- Trojan horse meets magic bullet to spawn a novel, highly effective drug delivery model. Lacko AG, Nair M, Paranjape S, Mooberry L, McConathy WJ. Chemotherapy. 2006;52(4):171-3. Epub 2006 May 10. Review. PMID:16691026
- Characterization of lecithin:cholesterol acyltransferase expressed in a human lung cell line. Lane SB, Tchedre KT, Nair MP, Thigpen AE, Lacko AG. Protein Expr Purif. 2004 Aug;36(2):157-64. PMID:1524903
- ApoA-1 Milano and regression of atherosclerosis. Kim H, Jacobson EL, Jacobson MK, Lacko AG. JAMA. 2004 Mar 17;291(11):1319; author reply 1320. No abstract available. PMID:15026388
- High density lipoprotein complexes as delivery vehicles for anticancer drugs. Lacko AG, Nair M, Paranjape S, Johnso S, McConathy WJ. Anticancer Res. 2002 Jul-Aug;22(4):2045-9. PMID:12174882