Histology

The Histology Core offers comprehensive support for histology services and training.
We provide a range of services, including equipment training, consultation, and assistance
with all aspects of the histology workflow.
Our core facility is equipped with state-of-the-art histology equipment to ensure high-quality sample preparation & imaging results.
The primary objective of this Core Facility is to cater to the research needs of the UNT Health and the broader scientific community in Fort Worth. We provide cutting-edge facilities that are open to faculty members, staff, and graduate students as well as external individuals and organizations enabling them to carry out their research effectively.
Histology Equipment
Tissue-Tek VIP AI Tissue Processor Tissue-Tek Cryo3 Flex Cryostat Leica UC7 Ultramicrotome Leica Microtome Leica Embedding station
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Contact us for more details about equipment, services, and scheduling time in the Histology Core.
Contact UsiLab
Log in to iLab to see a full list of equipment and schedule time in the Histology Core.
Login to iLabHistology Core FAQ
You can obtain more precise quotes for your project by reaching out to Tamara Mcinnis.
Trained users have 24/7 access to Histology Core equipment. Technical assistance is available on weekdays from 8 a.m. to 5 p.m.
Training is provided only to internal users who wish to use the histology core equipment on their own.
Q: What is this about?
A: This is an opportunity to participate in a training session on the Histology Core
equipment.
Q. What kind of training is offered and what are the costs?
A: We offer following training:
| Trainings | |||
| Paraffin embedded material | 2-3 hours (materials provided by the Core) + dedicated support as needed during real exp | Necessary equipment training included | $150 |
| OCT embedded material | 2-3 hours (materials provided by the Core) + dedicated support as needed during real exp | Necessary equipment training included | $150 |
| Plastic embedding material | 2-3 hours (materials provided by the Core) + dedicated support as needed during real exp | Necessary equipment training included | $150 |
| IHC | 2-3 hours hours (materials to be provided by the user) + dedicated support as needed during real exp | Necessary equipment training included | $150 |
Q: How do I book and make payment for my training?
A: Training is held as per demand. Please contact Tamara Mcinnis to schedule training and request training using iLab.
To request training through iLab...
- Login with your EUID and Password
- Go to Request Services tab
- Go to Request ?Histology Training? section and Initiate Request
- Fill out the form, complete the payment information and submit
Questions
- Contact Tamara Mcinnis, Senior Research Associate, Histology
- Contact Sharad Shrestha, Core Labs Director
Open-source image processing and analysis software
- Fiji : A distribution of ImageJ which includes many useful plugins contributed by the community.
- Icy : Used for a wide range of processing and analysis applications.
- CellProfiler : Used for high-throughput image analysis and data mining.
- KNIME : Used for high-throughput image analysis and data mining.
- QuPath : Used for digital pathology and whole slide image analysis.
- ilastik : Consists of powerful machine learning features needed to identify or classify challenging structures.
- napari : It is a fast, interactive, multi-dimensional image viewer for Python. It is designed for browsing, annotating, and analyzing large multi-dimensional images.
Bio-image processing and analysis learning resources
- Useful Bio-Image analysis YouTube videos.
- Quantifying microscopy images: Top 10 tips for image acquisition
- Quantitative Imaging for Colocalization Analysis (pdf)
- Avoiding Twisted Pixels: Ethical Guidelines for the Appropriate Use and Manipulation of Scienti?c Digital Images
Bio-imaging Networking
- The Center for Open Bioimage Analysis (COBA)
- The international network of cutting-edge bioimaging facilities and communities: (Exchange of Experience, Training, Shadowing, Working Groups)
Bio-imaging Sample Preparation
Bio-Safety Assessment:
The purpose of the bio-safety assessment is to identify potential hazards, and hence control measures that might be needed. This is to help ensure the health and safety of the researcher and of any other person that might be affected by the work. New researchers are required to submit a bio-safety assessment form during initial consultation.
- How can I start accessing the Histology Core?
- Email Tamara McInnis to
- Schedule a training with Core staff, get trained and use histology equipment by yourself.
- Schedule sample submission consultation session with Core staff, who will coordinate with you to image your sample.
- Email Tamara McInnis to
- How can I get access to histology instruments after hours?
- Only trained users are authorized to operate instrument independently after hours.
- Who to contact if I have any question?
- Contact Tamara McInnis
Recommended Sample Submission & Preparation Guideline:
- More information to come
Contributions to scientific output is an important metric for Core Labs, as it enables us to obtain financial and other support to ensure continuous high standards of operations to foster innovative research.
Users are encouraged to acknowledge Histology Core in presentations, posters, papers, and all other publications.
For example: ?We acknowledge [name of staff] in the UNT Health Histology Core for training and assistance on [following]?.
When to acknowledge or provide co-authorship
- Include an acknowledgement any time the staff member or the Core provides services that support your research
- If a staff member has made a significant intellectual contribution beyond routine sample analysis, please consider co-authorship
