Available Instrumentation

Examples of Collaborative Services and Available Instrumentation in the UNT System College of Pharmacy

NMR Spectrometer	Identify and characterize chemicals and compounds via 1H and 13C spectroscopy (1D and 2D)
TOF LC/MS	Identify chemical reaction products; verify compound identity via accurate mass for small molecules
QQQ LC/MS	Pharmacokinetic and pharmacodynamic studies of small molecules; other UHPLC applications where mass spectrometry detection of small molecules is required
Lyophilizer	Remove aqueous solvents from sample(s) by freeze drying
Powder X-ray Diffractometer	Analytical technique primarily used for phase identification of a crystalline material and can provide information on unit cell dimensions
UV/Vis Spectrophotometer	UV/Vis spectral analysis (cuvette)
Waters Arc HPLC System	Qualitative and quantitative analysis of chemical reactions and biochemical experiments
Dissolution Test System	Dissolution testing of drug formulations
Vertical Diffusion System	In vitro permeation studies for transdermal drug research
Zetasizer Ultra Particle Analyzer	Particle characterization
Mastersizer 3000E Particle Analyzer	Particle size distribution analysis by dynamic light scattering (DLS) on particles from 0.1µM up to 1000µm
RT-PCR System	Amplify DNA, quantitate DNA and mRNA
ChemiDoc Imaging System	UV/Vis detection and documentation for gel/Western imaging; DNA, RNA and protein analysis
Odyssey IR Scanner	Near IR (NIR) Western blot detection, also in-cell and on-cell Westerns, and visualization of Syto 60-stained nucleic acids in gels
Biological Safety Cabinet	Work space for culturing mammalian cells as well as experiments involving biohazardous materials
CO2 Incubators	Culture cells for biochemical and pharmaceutical experiments
Inverted-Stage Microscope with Digital Camera	Visual monitoring and digital documentation of cell cultures
Vi-Cell Analyzer	Determine cell number, cell size and cell viability using cuvettes
Image Cytometer	Determine cell number, cell size and cell viability using slide- based counting chambers
Fluorescence Microscopy	Digital photographic documentation and histological analysis of cultured cells and tissues
Multi-Mode Microplate Reader	Fluorescence, UV/Vis absorbance and luminescence-based microplate assays
Centrifuges	Centrifugation for cell culture and sample preparation
Dual-injector luminometer	Glow- and flash-based bioluminescence assays in 96-well plates
Water Purification System	Reagent quality water required for cell culture, chemical and biochemical experiments, and spectrophotometric analyses
OpenSPR	Surface plasmon resonance for binding kinetics and affinity studies
FTIR Spectrometer	Infrared spectral analysis
Differential Scanning Calorimeter	Thermoanalysis of compounds to provide structural information useful for compound identification and characterization
Thermogravimetric Analyzer	Method of thermal analysis in which the mass of a sample is measured over time as the temperature changes.

 

The Pharmaceutical Analysis Core Lab utilizes iLab for managing instrument reservations, use and fee-for-service requests. To register for an iLab account, please visit https://unthsc.ilab.agilent.com.
For more information please contact:
Donna Coyle	Yan Graf
817-735-0688	817-735-0679
Donna.Coyle@unthealth.edu	Yan.Graf@unthealth.edu

 

3500 Camp Bowie Blvd
Fort Worth, Texas 76107